BDBM50342474 (S)-cyclobutyl(3-(3-m-tolyl-1,2,4-oxadiazol-5-yl)piperidin-1-yl)methanone::CHEMBL1771621

SMILES Cc1cccc(c1)-c1noc(n1)[C@H]1CCCN(C1)C(=O)C1CCC1

InChI Key InChIKey=AURFQZURADYOGD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50342474   

TargetMetabotropic glutamate receptor 5(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50342474((S)-cyclobutyl(3-(3-m-tolyl-1,2,4-oxadiazol-5-yl)p...)
Affinity DataIC50: 700nMAssay Description:Negative allosteric modulator activity at mGluR5 receptor expressed in HEK293A cells assessed as inhibition of glutamate-induced calcium flux preincu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed