BDBM50342465 CHEMBL1771693::rac-cyclobutyl(2-(3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl)pyrrolidin-1-yl)methanone

SMILES Fc1ccc(cc1)-c1noc(n1)C1CCCN1C(=O)C1CCC1

InChI Key InChIKey=SKWHGYKYQAGZNU-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50342465   

TargetMetabotropic glutamate receptor 5(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50342465(rac-cyclobutyl(2-(3-(4-fluorophenyl)-1,2,4-oxadiaz...)
Affinity DataEC50:  2.70E+3nMAssay Description:Positive allosteric modulator activity at mGluR5 receptor expressed in HEK293A cells assessed as effect on glutamate-induced calcium flux preincubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed