BDBM50342448 CHEMBL1771646::cyclohexyl(2-(3-(3-fluorophenyl)-1,2,4-oxadiazol-5-yl)pyrrolidin-1-yl)methanone

SMILES Fc1cccc(c1)-c1noc(n1)C1CCCN1C(=O)C1CCCCC1

InChI Key InChIKey=JFRXMDANHVDUCO-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50342448   

TargetMetabotropic glutamate receptor 5(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50342448(cyclohexyl(2-(3-(3-fluorophenyl)-1,2,4-oxadiazol-5...)
Affinity DataEC50:  1.00E+4nMAssay Description:Positive allosteric modulator activity at mGluR5 receptor expressed in HEK293A cells assessed as effect on glutamate-induced calcium flux preincubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed