BDBM50342446 CHEMBL1771696::cyclopropyl(2-(3-(3-fluorophenyl)-1,2,4-oxadiazol-5-yl)pyrrolidin-1-yl)methanone

SMILES Fc1cccc(c1)-c1noc(n1)C1CCCN1C(=O)C1CC1

InChI Key InChIKey=PMXRCEMWMUJHLO-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50342446   

TargetMetabotropic glutamate receptor 5(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50342446(cyclopropyl(2-(3-(3-fluorophenyl)-1,2,4-oxadiazol-...)
Affinity DataEC50:  2.90E+3nMAssay Description:Positive allosteric modulator activity at mGluR5 receptor expressed in HEK293A cells assessed as effect on glutamate-induced calcium flux preincubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed