BDBM50342441 (R)-(3-fluorophenyl)(2-(3-(3-fluorophenyl)-1,2,4-oxadiazol-5-yl)piperidin-1-yl)methanone::CHEMBL1771689

SMILES Fc1cccc(c1)C(=O)N1CCCC[C@@H]1c1nc(no1)-c1cccc(F)c1

InChI Key InChIKey=IXTSWRCNBQFSPA-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50342441   

TargetMetabotropic glutamate receptor 5(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50342441((R)-(3-fluorophenyl)(2-(3-(3-fluorophenyl)-1,2,4-o...)
Affinity DataEC50:  460nMAssay Description:Positive allosteric modulator activity at mGluR5 receptor expressed in HEK293A cells assessed as effect on glutamate-induced calcium flux preincubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed