BDBM50342242 (S)-2-((2S,3S)-2-((S)-2-((S)-1-((S)-6-amino-2-((S)-2,6-diaminohexanamido)hexanoyl)pyrrolidine-2-carboxamido)-3-(4-hydroxyphenyl)propanamido)-3-methylpentanamido)-4-methylpentanoic acid::CHEMBL258221::H-Lys-Lys-Pro-Tyr-Ile-Leu-OH

SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCCN)NC(=O)[C@@H](N)CCCCN)C(=O)N[C@@H](CC(C)C)C(O)=O

InChI Key InChIKey=JDVIBJLNEIKOTF-UHFFFAOYSA-N

Data  2 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50342242   

TargetNeurotensin receptor type 2(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50342242((S)-2-((2S,3S)-2-((S)-2-((S)-1-((S)-6-amino-2-((S)...)
Affinity DataIC50: 0.950nMAssay Description:Displacement of 125I-[Tyr3]-NT from human NTS2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2020
Entry Details Article
PubMed
TargetNeurotensin receptor type 1(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50342242((S)-2-((2S,3S)-2-((S)-2-((S)-1-((S)-6-amino-2-((S)...)
Affinity DataIC50: 0.330nMAssay Description:Displacement of 125I-[Tyr3]-NT from human NTS1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2020
Entry Details Article
PubMed
TargetNeurotensin receptor type 1(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50342242((S)-2-((2S,3S)-2-((S)-2-((S)-1-((S)-6-amino-2-((S)...)
Affinity DataIC50: 0.0800nMAssay Description:Inhibition of human NTR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetNeurotensin receptor type 2(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50342242((S)-2-((2S,3S)-2-((S)-2-((S)-1-((S)-6-amino-2-((S)...)
Affinity DataIC50: 0.470nMAssay Description:Inhibition of human NTR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetNeurotensin receptor type 1(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50342242((S)-2-((2S,3S)-2-((S)-2-((S)-1-((S)-6-amino-2-((S)...)
Affinity DataKi:  2.70nMAssay Description:Displacement of [3H]neurotensin from human NTS1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetNeurotensin receptor type 2(Human)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50342242((S)-2-((2S,3S)-2-((S)-2-((S)-1-((S)-6-amino-2-((S)...)
Affinity DataKi:  6.10nMAssay Description:Displacement of [3H]NT from human NTS2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed