BDBM50342038 1-(2-Bromophenyl)-N-(4-cyanotetrahydro-2H-pyran-4-yl)-5-(4-methoxyphenyl)-4-methyl-1H-pyrazole-3-carboxamide::CHEMBL1765683

SMILES COc1ccc(cc1)-c1c(C)c(nn1-c1ccccc1Br)C(=O)NC1(CCOCC1)C#N

InChI Key InChIKey=ZVRXOXFSMYJETP-UHFFFAOYSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50342038   

TargetTranslocator protein(Rat)
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50342038(1-(2-Bromophenyl)-N-(4-cyanotetrahydro-2H-pyran-4-...)
Affinity DataKi:  29nMAssay Description:Displacement of [3H]PK11195 from TSPO receptor in rat kidney membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2013
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50342038(1-(2-Bromophenyl)-N-(4-cyanotetrahydro-2H-pyran-4-...)
Affinity DataKi:  62.2nMAssay Description:Displacement of [3H]CP55940 from CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2013
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50342038(1-(2-Bromophenyl)-N-(4-cyanotetrahydro-2H-pyran-4-...)
Affinity DataKi:  798nMAssay Description:Binding affinity to kappa opioid receptor by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2013
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50342038(1-(2-Bromophenyl)-N-(4-cyanotetrahydro-2H-pyran-4-...)
Affinity DataKi:  1.89E+3nMAssay Description:Displacement of [3H]CP55940 from CB2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50342038(1-(2-Bromophenyl)-N-(4-cyanotetrahydro-2H-pyran-4-...)
Affinity DataKi:  6.28E+3nMAssay Description:Binding affinity to 5HT2A receptor by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50342038(1-(2-Bromophenyl)-N-(4-cyanotetrahydro-2H-pyran-4-...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to 5HT1D receptor by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2013
Entry Details Article
PubMed
TargetD(1B) dopamine receptor(Human)
National Institute of Mental Health

Curated by ChEMBL
LigandPNGBDBM50342038(1-(2-Bromophenyl)-N-(4-cyanotetrahydro-2H-pyran-4-...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to opamine D5 receptor by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2013
Entry Details Article
PubMed