BDBM50341918 (2-heptylamino-1-phosphono-ethyl)-phosphonic acid::1-[(n-hept-1-ylamino)ethyl]-1,1-bisphosphonic acid::2-(heptylamino)ethane-1,1-diyldiphosphonic acid::CHEMBL261473

SMILES CCCCCCCNCC(P(=O)(O)O)P(=O)(O)O

InChI Key InChIKey=WRMHTOUCTOHPIY-UHFFFAOYSA-N

Data  7 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50341918   

TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50341918((2-heptylamino-1-phosphono-ethyl)-phosphonic acid ...)
Affinity DataIC50: 58nMAssay Description:Inhibition of Trypanosoma cruzi FPPS after 30 mins using [14C]IPP by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetFarnesyl diphosphate synthase(Toxoplasma gondii)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50341918((2-heptylamino-1-phosphono-ethyl)-phosphonic acid ...)
Affinity DataIC50: 95nMAssay Description:Inhibition of Toxoplasma gondii FPPSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50341918((2-heptylamino-1-phosphono-ethyl)-phosphonic acid ...)
Affinity DataIC50: 58nMAssay Description:Inhibition of Trypanosoma cruzi FPPSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSolanesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50341918((2-heptylamino-1-phosphono-ethyl)-phosphonic acid ...)
Affinity DataIC50: 1.69E+3nMAssay Description:Inhibition of Trypanosoma cruzi SPPSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetFarnesyl diphosphate synthase(Toxoplasma gondii)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50341918((2-heptylamino-1-phosphono-ethyl)-phosphonic acid ...)
Affinity DataIC50: 95nMAssay Description:Inhibition of Toxoplasma gondii FPPSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetFarnesyl diphosphate synthase(Toxoplasma gondii)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50341918((2-heptylamino-1-phosphono-ethyl)-phosphonic acid ...)
Affinity DataIC50: 95nMAssay Description:Inhibition of Toxoplasma gondii FPPS using DMAPP as substrate incubated for 30 mins measured by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetFarnesyl diphosphate synthase(Trypanosoma cruzi)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50341918((2-heptylamino-1-phosphono-ethyl)-phosphonic acid ...)
Affinity DataIC50: 58nMAssay Description:Inhibition of Trypanosoma cruzi FPPS using DMAPP as substrate incubated for 30 mins measured by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)