BDBM50341802 (1S,2R,3R)-2-Methyl-3-phenyl-1-(1,2,3,4-tetrahydropyrazino-[1,2-a]benzimidazole-2-sulfonylamino)cyclopropanecarboxylicAcid::CHEMBL1767004

SMILES C[C@@H]1[C@H](c2ccccc2)[C@]1(NS(=O)(=O)N1CCn2c(C1)nc1ccccc21)C(O)=O

InChI Key InChIKey=OGCHVEMYHSXDJE-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50341802   

TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50341802((1S,2R,3R)-2-Methyl-3-phenyl-1-(1,2,3,4-tetrahydro...)
Affinity DataIC50: 92nMAssay Description:Inhibition of human recombinant aggrecanase 2 after 150 mins by fluorescence plate readerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetMatrix metalloproteinase-14(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50341802((1S,2R,3R)-2-Methyl-3-phenyl-1-(1,2,3,4-tetrahydro...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of human recombinant MMP14 after 60 mins by fluorescence plate readerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50341802((1S,2R,3R)-2-Methyl-3-phenyl-1-(1,2,3,4-tetrahydro...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant MMP1 after 60 mins by fluorescence plate readerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50341802((1S,2R,3R)-2-Methyl-3-phenyl-1-(1,2,3,4-tetrahydro...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant TACE after 60 mins by fluorescence plate readerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed