BDBM50341676 (E)-3-(4-hydroxybenzylidene)chroman-4-one::CHEMBL1383041

SMILES Oc1ccc(\C=C2/COc3ccccc3C2=O)cc1

InChI Key InChIKey=NIGIWYGQQJWVST-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50341676   

TargetAmine oxidase [flavin-containing] B(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50341676((E)-3-(4-hydroxybenzylidene)chroman-4-one | CHEMBL...)
Affinity DataIC50: 55.4nMAssay Description:Inhibition of human recombinant MAO-B expressed in baculovirus infected BTI-TN-5B1-4 insect sells assessed as hydrogen peroxide production by fluorim...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50341676((E)-3-(4-hydroxybenzylidene)chroman-4-one | CHEMBL...)
Affinity DataIC50: 5.50E+4nMAssay Description:Inhibition of MAO-B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetMacrophage migration inhibitory factor(Human)
University of Pecs

Curated by ChEMBL
LigandPNGBDBM50341676((E)-3-(4-hydroxybenzylidene)chroman-4-one | CHEMBL...)
Affinity DataIC50: 1.27E+5nMAssay Description:Inhibition of human recombinant MIF ketonase activity using phenylpyruvate as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetMacrophage migration inhibitory factor(Human)
University of Pecs

Curated by ChEMBL
LigandPNGBDBM50341676((E)-3-(4-hydroxybenzylidene)chroman-4-one | CHEMBL...)
Affinity DataIC50: 7.27E+4nMAssay Description:Inhibition of human recombinant MIF enolase activity using phenylpyruvate as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed