BDBM50341628 3-(4-Acetylpiperazin-1-yl)-5-(3-nitrobenzylamino)-7-(trifluoromethyl)quinoline::CHEMBL1766529

SMILES CC(=O)N1CCN(CC1)c1cnc2cc(cc(NCc3cccc(c3)[N+]([O-])=O)c2c1)C(F)(F)F

InChI Key InChIKey=DORMVCLDXDMKMM-UHFFFAOYSA-N

Data  15 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 50341628   

TargetMacrophage-stimulating protein receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50341628(3-(4-Acetylpiperazin-1-yl)-5-(3-nitrobenzylamino)-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of RONMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50341628(3-(4-Acetylpiperazin-1-yl)-5-(3-nitrobenzylamino)-...)
Affinity DataIC50: 0.950nMAssay Description:Inhibition of purified recombinant c-Met after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50341628(3-(4-Acetylpiperazin-1-yl)-5-(3-nitrobenzylamino)-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Flt-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50341628(3-(4-Acetylpiperazin-1-yl)-5-(3-nitrobenzylamino)-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50341628(3-(4-Acetylpiperazin-1-yl)-5-(3-nitrobenzylamino)-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of c-KitMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50341628(3-(4-Acetylpiperazin-1-yl)-5-(3-nitrobenzylamino)-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDGFRalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50341628(3-(4-Acetylpiperazin-1-yl)-5-(3-nitrobenzylamino)-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of RETMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50341628(3-(4-Acetylpiperazin-1-yl)-5-(3-nitrobenzylamino)-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50341628(3-(4-Acetylpiperazin-1-yl)-5-(3-nitrobenzylamino)-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ErbB2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50341628(3-(4-Acetylpiperazin-1-yl)-5-(3-nitrobenzylamino)-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of c-SrcMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50341628(3-(4-Acetylpiperazin-1-yl)-5-(3-nitrobenzylamino)-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of AblMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetEphrin type-A receptor 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50341628(3-(4-Acetylpiperazin-1-yl)-5-(3-nitrobenzylamino)-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of EPH-A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetEphrin type-B receptor 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50341628(3-(4-Acetylpiperazin-1-yl)-5-(3-nitrobenzylamino)-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of EPH-B2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50341628(3-(4-Acetylpiperazin-1-yl)-5-(3-nitrobenzylamino)-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50341628(3-(4-Acetylpiperazin-1-yl)-5-(3-nitrobenzylamino)-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FGFR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed