BDBM50341437 2-(1-Naphthylsulfonyl)-1,2,3,4-tetrahydro-6-isoquinolinol::CHEMBL1766964

SMILES Oc1ccc2CN(CCc2c1)S(=O)(=O)c1cccc2ccccc12

InChI Key InChIKey=RYKKOMQBLXQKGK-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50341437   

TargetEstrogen receptor beta(Human)
Technische Universiteit Eindhoven

Curated by ChEMBL
LigandPNGBDBM50341437(2-(1-Naphthylsulfonyl)-1,2,3,4-tetrahydro-6-isoqui...)
Affinity DataEC50:  6.00E+4nMAssay Description:Agonist activity at human N-terminal His6-tagged ERbeta receptor LBD expressed in Escherichia coli BL21 (DE3) assessed as induction of SRC1 peptide r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Technische Universiteit Eindhoven

Curated by ChEMBL
LigandPNGBDBM50341437(2-(1-Naphthylsulfonyl)-1,2,3,4-tetrahydro-6-isoqui...)
Affinity DataEC50:  7.00E+5nMAssay Description:Agonist activity at human N-terminal His6-tagged ERalpha receptor LBD expressed in Escherichia coli BL21 (DE3) assessed as induction of SRC1 peptide ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed