BDBM50341432 1,3-Diphenethylpyrimidine-2,4,6(1H,3H,5H)-trione::CHEMBL1412368

SMILES O=C1CC(=O)N(CCc2ccccc2)C(=O)N1CCc1ccccc1

InChI Key InChIKey=HSNSQMGDNFKEES-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50341432   

TargetCytochrome P450 1A2(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50341432(1,3-Diphenethylpyrimidine-2,4,6(1H,3H,5H)-trione |...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP1A2 in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50341432(1,3-Diphenethylpyrimidine-2,4,6(1H,3H,5H)-trione |...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50341432(1,3-Diphenethylpyrimidine-2,4,6(1H,3H,5H)-trione |...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP2C19 in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50341432(1,3-Diphenethylpyrimidine-2,4,6(1H,3H,5H)-trione |...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50341432(1,3-Diphenethylpyrimidine-2,4,6(1H,3H,5H)-trione |...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed