BDBM50341403 CHEMBL4173265

SMILES NS(=O)(=O)c1ccc(Nc2ncc3C(=O)CCCc3n2)cc1

InChI Key InChIKey=LJWVCXMFRNTURZ-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50341403   

TargetCarbonic anhydrase 9(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50341403(CHEMBL4173265)
Affinity DataKi:  0.550nMAssay Description:Inhibition of recombinant human CA9 preincubated for 15 mins by phenol red dye-based stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50341403(CHEMBL4173265)
Affinity DataKi:  5.20nMAssay Description:Inhibition of recombinant human CA2 preincubated for 15 mins by phenol red dye-based stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50341403(CHEMBL4173265)
Affinity DataKi:  64nMAssay Description:Inhibition of recombinant human cytosolic CA1 preincubated for 15 mins by phenol red dye-based stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 4(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50341403(CHEMBL4173265)
Affinity DataKi:  73nMAssay Description:Inhibition of recombinant human CA4 preincubated for 15 mins by phenol red dye-based stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed