BDBM50341378 CHEBI:9921::Valerenic Acid

SMILES [H][C@]12CCC(C)=C1[C@@H](CC[C@H]2C)\C=C(/C)C(O)=O

InChI Key InChIKey=FEBNTWHYQKGEIQ-UHFFFAOYSA-N

Data  11 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50341378   

TargetRetinoic acid receptor RXR-beta(Human)
Swiss Federal Institute of Technology (Eth)

Curated by ChEMBL
LigandPNGBDBM50341378(CHEBI:9921 | Valerenic Acid)
Affinity DataEC50:  5.20E+3nMAssay Description:Transactivation of human Gal4-fused RXRbeta LBD expressed in HEK293T cells after 12 to 14 hrs by dual-glo luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-gamma(Human)
Swiss Federal Institute of Technology (Eth)

Curated by ChEMBL
LigandPNGBDBM50341378(CHEBI:9921 | Valerenic Acid)
Affinity DataEC50:  4.30E+4nMAssay Description:Transactivation of human Gal4-fused RXRgamma LBD expressed in HEK293T cells after 12 to 14 hrs by dual-glo luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-alpha(Human)
Swiss Federal Institute of Technology (Eth)

Curated by ChEMBL
LigandPNGBDBM50341378(CHEBI:9921 | Valerenic Acid)
Affinity DataEC50:  2.70E+4nMAssay Description:Transactivation of human Gal4-fused RXRalpha LBD expressed in HEK293T cells after 12 to 14 hrs by dual-glo luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
LigandPNGBDBM50341378(CHEBI:9921 | Valerenic Acid)
Affinity DataEC50:  1.90E+4nMAssay Description:Positive allosteric modulation of GABA-A alpha1beta3gamma2S receptor (unknown origin) expressed in Xenopus laevis oocytes assessed as increase in GAB...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
LigandPNGBDBM50341378(CHEBI:9921 | Valerenic Acid)
Affinity DataEC50:  1.26E+4nMAssay Description:Positive allosteric modulation of GABAA alpha1beta2gamma2 receptor (unknown origin) stably expressed in CHO cells assessed as activation of GABA-indu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetRetinoic acid receptor RXR-alpha(Human)
Swiss Federal Institute of Technology (Eth)

Curated by ChEMBL
LigandPNGBDBM50341378(CHEBI:9921 | Valerenic Acid)
Affinity DataEC50:  2.70E+4nMAssay Description:Agonist activity at RXRalpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetRetinoic acid receptor RXR-beta(Human)
Swiss Federal Institute of Technology (Eth)

Curated by ChEMBL
LigandPNGBDBM50341378(CHEBI:9921 | Valerenic Acid)
Affinity DataEC50:  5.20E+3nMAssay Description:Agonist activity at RXRbeta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetRetinoic acid receptor RXR-gamma(Human)
Swiss Federal Institute of Technology (Eth)

Curated by ChEMBL
LigandPNGBDBM50341378(CHEBI:9921 | Valerenic Acid)
Affinity DataEC50:  4.30E+4nMAssay Description:Agonist activity at RXRgamma (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetRetinoic acid receptor RXR-alpha(Human)
Swiss Federal Institute of Technology (Eth)

Curated by ChEMBL
LigandPNGBDBM50341378(CHEBI:9921 | Valerenic Acid)
Affinity DataEC50:  2.70E+4nMAssay Description:Agonist activity at human GAL4-fused RXRalpha LBD expressed in human HEK293T cells cotransfected with pFR-Luc and pRL-SV40 assessed as increase in lu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetRetinoic acid receptor RXR-beta(Human)
Swiss Federal Institute of Technology (Eth)

Curated by ChEMBL
LigandPNGBDBM50341378(CHEBI:9921 | Valerenic Acid)
Affinity DataEC50:  5.00E+3nMAssay Description:Agonist activity at human GAL4-fused RXRbeta LBD expressed in human HEK293T cells cotransfected with pFR-Luc and pRL-SV40 assessed as increase in luc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetRetinoic acid receptor RXR-gamma(Human)
Swiss Federal Institute of Technology (Eth)

Curated by ChEMBL
LigandPNGBDBM50341378(CHEBI:9921 | Valerenic Acid)
Affinity DataEC50:  4.30E+4nMAssay Description:Agonist activity at human GAL4-fused RXRgamma LBD expressed in human HEK293T cells cotransfected with pFR-Luc and pRL-SV40 assessed as increase in lu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed