BDBM50340913 (4-amino-2-(pyridin-4-ylamino)thiazol-5-yl)(2-methoxyphenyl)methanone::CHEMBL1761802

SMILES COc1ccccc1C(=O)c1sc(Nc2ccncc2)nc1N

InChI Key InChIKey=RSPXQCXRWMXEAA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50340913   

TargetCyclin-dependent kinase 5 activator 1(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50340913((4-amino-2-(pyridin-4-ylamino)thiazol-5-yl)(2-meth...)
Affinity DataIC50: 60nMAssay Description:Inhibition of CDK5/p25 assessed as [33P]gamma-ATP incorporation into peptide PKTPKKAKKL substrate after 45 mins by scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed