BDBM50340611 CHEMBL1761566::N-(4-(3-morpholino-1H-1,2,4-triazol-1-yl)phenyl)-8-(thiazol-2-yl)quinazolin-2-amine

SMILES C1CN(CCO1)c1ncn(n1)-c1ccc(Nc2ncc3cccc(-c4nccs4)c3n2)cc1

InChI Key InChIKey=RQUGSKZRACGFFU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50340611   

TargetMitogen-activated protein kinase 10(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50340611(N-(4-(3-morpholino-1H-1,2,4-triazol-1-yl)phenyl)-8...)
Affinity DataIC50: 7nMAssay Description:Inhibition of JNK3 by HRTFMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50340611(N-(4-(3-morpholino-1H-1,2,4-triazol-1-yl)phenyl)-8...)
Affinity DataIC50: 30nMAssay Description:Inhibition of JNK1 by HRTFMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetTranscription factor Jun(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50340611(N-(4-(3-morpholino-1H-1,2,4-triazol-1-yl)phenyl)-8...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of c-JunMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed