BDBM50340338 CHEMBL1760947::N-(2-(6-Methoxy-1H-pyrrolo[2,3-b]pyridin-1-yl)ethyl)butyramide

SMILES CCCC(=O)NCCn1ccc2ccc(OC)nc12

InChI Key InChIKey=SRFKFUXRQNAXPP-UHFFFAOYSA-N

Data  2 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50340338   

TargetMelatonin receptor type 1B(Human)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50340338(N-(2-(6-Methoxy-1H-pyrrolo[2,3-b]pyridin-1-yl)ethy...)
Affinity DataEC50:  0.700nMAssay Description:Agonist activity at human MT2 receptor expressed in CHO cells by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetMelatonin receptor type 1A(Human)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50340338(N-(2-(6-Methoxy-1H-pyrrolo[2,3-b]pyridin-1-yl)ethy...)
Affinity DataEC50:  2.10nMAssay Description:Agonist activity at human MT1 receptor expressed in CHO cells by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Human)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50340338(N-(2-(6-Methoxy-1H-pyrrolo[2,3-b]pyridin-1-yl)ethy...)
Affinity DataKi:  0.300nMAssay Description:Displacement of 2-[125I]-iodomelatonin from human MT2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetMelatonin receptor type 1A(Human)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50340338(N-(2-(6-Methoxy-1H-pyrrolo[2,3-b]pyridin-1-yl)ethy...)
Affinity DataKi:  1.30nMAssay Description:Displacement of 2-[125I]-iodomelatonin from human MT1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed