BDBM50340325 CHEMBL1760945::N-(2-(6-Methoxy-1H-pyrrolo[2,3-b]pyridin-1-yl)ethyl)acetamide

SMILES COc1ccc2ccn(CCNC(C)=O)c2n1

InChI Key InChIKey=GPYJQMJXDIABBK-UHFFFAOYSA-N

Data  4 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50340325   

TargetMelatonin receptor type 1A(Human)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50340325(N-(2-(6-Methoxy-1H-pyrrolo[2,3-b]pyridin-1-yl)ethy...)
Affinity DataEC50:  4nMAssay Description:Agonist activity at human MT1 receptor expressed in CHO cells by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Human)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50340325(N-(2-(6-Methoxy-1H-pyrrolo[2,3-b]pyridin-1-yl)ethy...)
Affinity DataEC50:  2.10nMAssay Description:Agonist activity at human MT2 receptor expressed in CHO cells by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Human)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50340325(N-(2-(6-Methoxy-1H-pyrrolo[2,3-b]pyridin-1-yl)ethy...)
Affinity DataKi:  0.600nMAssay Description:Agonist activity at MT2 receptor (unknown origin) expressed in HEK293 cells by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Human)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50340325(N-(2-(6-Methoxy-1H-pyrrolo[2,3-b]pyridin-1-yl)ethy...)
Affinity DataKi:  0.600nMAssay Description:Displacement of 2-[125I]-iodomelatonin from human MT2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetMelatonin receptor type 1A(Human)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50340325(N-(2-(6-Methoxy-1H-pyrrolo[2,3-b]pyridin-1-yl)ethy...)
Affinity DataKi:  1.40nMAssay Description:Agonist activity at MT1 receptor (unknown origin) expressed in HEK293 cells by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetMelatonin receptor type 1A(Human)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50340325(N-(2-(6-Methoxy-1H-pyrrolo[2,3-b]pyridin-1-yl)ethy...)
Affinity DataKi:  1.40nMAssay Description:Displacement of 2-[125I]-iodomelatonin from human MT1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed