BDBM50339934 1,1'-(3,3'-(biphenyl-4,4'-diyl)bis(propane-3,1-diyl))bis(3,4-dimethylpyridinium)bromide::CHEMBL599735

SMILES Cc1cc[n+](CCCc2ccc(cc2)-c2ccc(CCC[n+]3ccc(C)c(C)c3)cc2)cc1C

InChI Key InChIKey=AKEWRXXBJJCYIL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50339934   

TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50339934(1,1'-(3,3'-(biphenyl-4,4'-diyl)bis(propane-3,1-diy...)
Affinity DataIC50: 4.20nMAssay Description:Antagonist activity at alpha9/alpha10 nAChR expressed in Xenopus oocyte assessed as inhibition of ACh-gated current by voltage clamp electrophysiolog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50339934(1,1'-(3,3'-(biphenyl-4,4'-diyl)bis(propane-3,1-diy...)
Affinity DataIC50: 1.51E+3nMAssay Description:Antagonist activity at alpha7 nAChR expressed in Xenopus oocyte assessed as inhibition of ACh-gated current by voltage clamp electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed