BDBM50339601 2-(3-chloro-4-hydroxyphenyl)-N-(4-sulfamoylphenethyl)acetamide::2-(3-chloro-4-hydroxyphenyl)-N-[2-(4-sulfamoylphenyl)ethyl]acetamide::CHEMBL606453

SMILES c1cc(ccc1CCNC(=O)Cc2ccc(c(c2)Cl)O)S(=O)(=O)N

InChI Key InChIKey=MALIONKMKPITBV-UHFFFAOYSA-N

Data  6 KI

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50339601   

TargetCarbonic anhydrase 2(Human)
Griffith University

Curated by ChEMBL
LigandPNGBDBM50339601(2-(3-chloro-4-hydroxyphenyl)-N-(4-sulfamoylpheneth...)
Affinity DataKi:  18nMAssay Description:Inhibition of human recombinant alpha-carbonic anhydrase 2 after 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 1(Human)
Griffith University

Curated by ChEMBL
LigandPNGBDBM50339601(2-(3-chloro-4-hydroxyphenyl)-N-(4-sulfamoylpheneth...)
Affinity DataKi:  700nMAssay Description:Inhibition of human recombinant alpha-carbonic anhydrase 1 after 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase(Cryptococcus neoformans var. grubii (Filobasidiell...)
Griffith University

Curated by ChEMBL
LigandPNGBDBM50339601(2-(3-chloro-4-hydroxyphenyl)-N-(4-sulfamoylpheneth...)
Affinity DataKi:  740nMAssay Description:Inhibition of Cryptococcus neoformans recombinant Can2 beta-carbonic anhydrase after 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase(Yeast)
Griffith University

Curated by ChEMBL
LigandPNGBDBM50339601(2-(3-chloro-4-hydroxyphenyl)-N-(4-sulfamoylpheneth...)
Affinity DataKi:  790nMAssay Description:Inhibition of Candida albicans recombinant Nce103 beta-carbonic anhydrase after 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Griffith University

Curated by ChEMBL
LigandPNGBDBM50339601(2-(3-chloro-4-hydroxyphenyl)-N-(4-sulfamoylpheneth...)
Affinity DataKi:  850nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant Rv3273 beta-carbonic anhydrase after 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetBeta-carbonic anhydrase 1(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Griffith University

Curated by ChEMBL
LigandPNGBDBM50339601(2-(3-chloro-4-hydroxyphenyl)-N-(4-sulfamoylpheneth...)
Affinity DataKi:  1.16E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant Rv1284 beta-carbonic anhydrase after 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed