BDBM50339468 3-{4-[(2'-Methylbiphenyl-3-yl)methoxy]phenyl}propanic Acid::CHEMBL1688465

SMILES Cc1ccccc1-c1cccc(COc2ccc(CCC(O)=O)cc2)c1

InChI Key InChIKey=UYOFBWPHHSPSSM-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50339468   

TargetFree fatty acid receptor 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50339468(3-{4-[(2'-Methylbiphenyl-3-yl)methoxy]phenyl}propa...)
Affinity DataEC50:  27nMAssay Description:Agonist activity against human GPR40 expressed in CHO cells assessed as increase in intracellular calcium level by FLIPR assay in presence of 0.1% BS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50339468(3-{4-[(2'-Methylbiphenyl-3-yl)methoxy]phenyl}propa...)
Affinity DataEC50:  16.6nMAssay Description:Agonist activity at FFAR1 expressed in HEK 293 cells assessed as beta-arrestin recruitment after 30 mins by BRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetFree fatty acid receptor 4(Human)
University of Southern Denmark

Curated by ChEMBL
LigandPNGBDBM50339468(3-{4-[(2'-Methylbiphenyl-3-yl)methoxy]phenyl}propa...)
Affinity DataEC50:  8.71E+3nMAssay Description:Agonist activity at GPR120 expressed in HEK 293 cells assessed as beta-arrestin recruitment after 5 mins by BRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed