BDBM50339439 (+/-)-cis-2-Benzyl-3-(4-chlorophenyl)-3-(4-hydroxycyclopent-2-enyloxy)isoindolin-1-one::CHEMBL1688254::US8618158, NU8298

SMILES O[C@H]1C[C@@H](OC2(N(Cc3ccccc3)C(=O)c3ccccc23)c2ccc(Cl)cc2)C=C1

InChI Key InChIKey=KPBNGPMEKAVOEK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50339439   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Cancer Research Technology

US Patent
LigandPNGBDBM50339439(CHEMBL1688254 | US8618158, NU8298 | (+/-)-cis-2-Be...)
Affinity DataIC50: 2.30E+3nMT: 2°CAssay Description:Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2014
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Cancer Research Technology

US Patent
LigandPNGBDBM50339439(CHEMBL1688254 | US8618158, NU8298 | (+/-)-cis-2-Be...)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed