BDBM50339437 (+/-)-3-(4-chlorophenyl)-3-((cis)-3-hydroxycyclopentyloxy)-2-(4-nitrobenzyl)isoindolin-1-one::CHEMBL1688252

SMILES O[C@@H]1CC[C@@H](C1)OC1(N(Cc2ccc(cc2)[N+]([O-])=O)C(=O)c2ccccc12)c1ccc(Cl)cc1

InChI Key InChIKey=RTMYOLAVEDNGOT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50339437   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50339437((+/-)-3-(4-chlorophenyl)-3-((cis)-3-hydroxycyclope...)
Affinity DataIC50: 400nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed