BDBM50339380 (+/-)-3-(4-Chlorophenyl)-2-((S)-1-(4-chlorophenyl)ethyl)-3-((1-(hydroxymethyl)cyclopropyl)methoxy)isoindolin-1-one::CHEMBL1688285::US8618158, NU8419

SMILES C[C@H](N1C(=O)c2ccccc2C1(OCC1(CO)CC1)c1ccc(Cl)cc1)c1ccc(Cl)cc1

InChI Key InChIKey=IYUMLCRMDKLSQE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50339380   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Cancer Research Technology

US Patent
LigandPNGBDBM50339380(CHEMBL1688285 | US8618158, NU8419 | (+/-)-3-(4-Chl...)
Affinity DataIC50: 8.90E+3nMT: 2°CAssay Description:Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2014
Entry Details
Go to US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Cancer Research Technology

US Patent
LigandPNGBDBM50339380(CHEMBL1688285 | US8618158, NU8419 | (+/-)-3-(4-Chl...)
Affinity DataIC50: 8.90E+3nMAssay Description:Inhibition of Mdm2 -p53 protein interaction by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed