BDBM50339243 (1S,2R)-N-((2S)-1-(1-amino-3-(4-fluorophenyl)-1-oxopropan-2-ylamino)-3-(1H-indol-3-yl)-1-oxopropan-2-yl)-2-(2-amino-3-(4-hydroxy-3,5-dimethylphenyl)propanamido)cyclohexanecarboxamide::CHEMBL1689545

SMILES Cc1cc(CC(N)C(=O)N[C@@H]2CCCC[C@@H]2C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)NC(Cc2ccc(F)cc2)C(N)=O)cc(C)c1O

InChI Key InChIKey=KHUWTVYBCSURGW-UHFFFAOYSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50339243   

TargetMu-type opioid receptor(Rat)
Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50339243((1S,2R)-N-((2S)-1-(1-amino-3-(4-fluorophenyl)-1-ox...)
Affinity DataEC50:  8.10nMAssay Description:Agonist activity at mu opioid receptor in rat brain membrane by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50339243((1S,2R)-N-((2S)-1-(1-amino-3-(4-fluorophenyl)-1-ox...)
Affinity DataKi:  11.1nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membrane homogenate by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50339243((1S,2R)-N-((2S)-1-(1-amino-3-(4-fluorophenyl)-1-ox...)
Affinity DataKi:  2.64E+3nMAssay Description:Displacement of [3H][Ile5,6]deltorphin2 from delta opioid receptor in rat brain membrane homogenate by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed