BDBM50338940 CHEMBL1685040::N-(4-(N-(5-tert-Butyl-1,3,4-thiadiazol-2-yl)sulfamoyl)phenyl)decanamide::US9320734, 119

SMILES CCCCCCCCCC(=O)Nc1ccc(cc1)S(=O)(=O)Nc1nnc(s1)C(C)(C)C

InChI Key InChIKey=UTDKUUJAGJRRIW-UHFFFAOYSA-N

Data  1 KI  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50338940   

TargetRAC-alpha serine/threonine-protein kinase [1-123](Human)
The University of Texas System

US Patent
LigandPNGBDBM50338940(N-(4-(N-(5-tert-Butyl-1,3,4-thiadiazol-2-yl)sulfam...)
Affinity DataKd:  2.84E+5nMAssay Description:SPR interaction analyses were performed with a Biacore 2000, using Biacore 2000 Control Software v3.2 and BIAevaluation v4.1 analysis software (Biaco...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2017
Entry Details
Go to US Patent

TargetRAC-alpha serine/threonine-protein kinase [1-123](Human)
The University of Texas System

US Patent
LigandPNGBDBM50338940(N-(4-(N-(5-tert-Butyl-1,3,4-thiadiazol-2-yl)sulfam...)
Affinity DataKd:  2.81E+5nMAssay Description:SPR interaction analyses were performed with a Biacore 2000, using Biacore 2000 Control Software v3.2 and BIAevaluation v4.1 analysis software (Biaco...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2017
Entry Details
Go to US Patent

TargetRAC-alpha serine/threonine-protein kinase(Mouse)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50338940(N-(4-(N-(5-tert-Butyl-1,3,4-thiadiazol-2-yl)sulfam...)
Affinity DataKi:  1.20E+4nMAssay Description:Displacement of biotinylated phosphatidylinositol-3,4,5-phosphate from mouse AKT1 PH domain by surface plasmon resonance competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed