BDBM50338818 CHEMBL1684582::N-(4-(((5R)-5-((S)-hydroxy(phenyl)methyl)pyrrolidin-2-yl)methyl)phenyl)-4-(4-(4-(trifluoromethyl)phenyl)thiazol-2-yl)benzenesulfonamide

SMILES O[C@H]([C@H]1CCC(Cc2ccc(NS(=O)(=O)c3ccc(cc3)-c3nc(cs3)-c3ccc(cc3)C(F)(F)F)cc2)N1)c1ccccc1

InChI Key InChIKey=CVNUDPVQPWCUGZ-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50338818   

TargetBeta-2 adrenergic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50338818(N-(4-(((5R)-5-((S)-hydroxy(phenyl)methyl)pyrrolidi...)
Affinity DataIC50: 2.79E+3nMAssay Description:Agonist activity at human beta2 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetBeta-3 adrenergic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50338818(N-(4-(((5R)-5-((S)-hydroxy(phenyl)methyl)pyrrolidi...)
Affinity DataEC50:  1.31E+3nMAssay Description:Agonist activity at human beta3 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50338818(N-(4-(((5R)-5-((S)-hydroxy(phenyl)methyl)pyrrolidi...)
Affinity DataIC50: 1.52E+3nMAssay Description:Agonist activity at human beta1 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed