BDBM50338711 CHEMBL1684218::N-cyclopropyl-3-(4-(2-(dimethylamino)ethylthio)-6-(1H-pyrazol-4-yl)quinazolin-2-yl)chroman-6-carboxamide

SMILES CN(C)CCSc1nc(nc2ccc(cc12)-c1cn[nH]c1)C1COc2ccc(cc2C1)C(=O)NC1CC1

InChI Key InChIKey=YODMOGHHXNYZIW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50338711   

TargetRho-associated protein kinase 2(Human)
Translational Research Institute

Curated by ChEMBL
LigandPNGBDBM50338711(N-cyclopropyl-3-(4-(2-(dimethylamino)ethylthio)-6-...)
Affinity DataIC50: 6nMAssay Description:Inhibition of ROCK2 by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed