BDBM50338520 1-(4-chlorobenzyl)-N-(diaminomethylene)-5-methyl-1H-imidazole-4-carboxamide::CHEMBL1683575

SMILES Cc1c(ncn1Cc1ccc(Cl)cc1)C(=O)NC(N)=N

InChI Key InChIKey=MBFRJCJPZMFFMU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50338520   

TargetAcyl-CoA desaturase 1(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50338520(1-(4-chlorobenzyl)-N-(diaminomethylene)-5-methyl-1...)
Affinity DataIC50: 94nMAssay Description:Inhibition of rat liver SCD1 using [3H]-stearoylCoAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetStearoyl-CoA desaturase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50338520(1-(4-chlorobenzyl)-N-(diaminomethylene)-5-methyl-1...)
Affinity DataIC50: 217nMAssay Description:Inhibition of human SCD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetAcyl-CoA desaturase 1(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50338520(1-(4-chlorobenzyl)-N-(diaminomethylene)-5-methyl-1...)
Affinity DataIC50: 68nMAssay Description:Inhibition of rat liver SCD1 assessed as formation of deuterated oleoylCoA by HTMS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed