BDBM50338356 (+)-7-[1-Hydroxy-1-(1H-imidazol-4-yl)-2-methylpropyl]-1,2-dihydro-3H-benzo[e]isoindol-3-one::(-)-7-[1-Hydroxy-1-(1H-imidazol-4-yl)-2-methylpropyl]-1,2-dihydro-3H-benzo[e]isoindol-3-one::CHEMBL1682900::rac-7-[1-Hydroxy-1-(1H-imidazol-4-yl)-2-methylpropyl]-1,2-dihydro-3H-benzo[e]isoindol-3-one

SMILES CC(C)C(O)(c1cnc[nH]1)c1ccc2c3CNC(=O)c3ccc2c1

InChI Key InChIKey=JJPKQUVDOTUNRO-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50338356   

TargetSteroid 11-beta-monooxygenase(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50338356((+)-7-[1-Hydroxy-1-(1H-imidazol-4-yl)-2-methylprop...)
Affinity DataIC50: 13nMAssay Description:Inhibition of 11-hydroxylase activity in Sprague-Dawley rat adrenal glandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50338356((+)-7-[1-Hydroxy-1-(1H-imidazol-4-yl)-2-methylprop...)
Affinity DataIC50: 15nMAssay Description:Inhibition of 17,20 lyase activity in humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50338356((+)-7-[1-Hydroxy-1-(1H-imidazol-4-yl)-2-methylprop...)
Affinity DataIC50: 15nMAssay Description:Inhibition of 17,20 lyase activity in humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50338356((+)-7-[1-Hydroxy-1-(1H-imidazol-4-yl)-2-methylprop...)
Affinity DataIC50: 18nMAssay Description:Inhibition of 17,20 lyase activity in humanMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50338356((+)-7-[1-Hydroxy-1-(1H-imidazol-4-yl)-2-methylprop...)
Affinity DataIC50: 180nMAssay Description:Inhibition of 17,20 lyase activity in Sprague-Dawley rat testicular microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetSteroid 11-beta-monooxygenase(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50338356((+)-7-[1-Hydroxy-1-(1H-imidazol-4-yl)-2-methylprop...)
Affinity DataIC50: 13nMAssay Description:Inhibition of 11-hydroxylase activity in Sprague-Dawley rat adrenal glandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50338356((+)-7-[1-Hydroxy-1-(1H-imidazol-4-yl)-2-methylprop...)
Affinity DataIC50: 6.70E+3nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50338356((+)-7-[1-Hydroxy-1-(1H-imidazol-4-yl)-2-methylprop...)
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50338356((+)-7-[1-Hydroxy-1-(1H-imidazol-4-yl)-2-methylprop...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2013
Entry Details Article
PubMed