BDBM50338281 CHEMBL1681791::methyl 2-(2-(isoquinolin-5-yl)acetamido)-4-methylthiophene-3-carboxylate

SMILES COC(=O)c1c(C)csc1NC(=O)Cc1cccc2cnccc12

InChI Key InChIKey=YAOWLMDOOICXCZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50338281   

TargetMitogen-activated protein kinase 9(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50338281(methyl 2-(2-(isoquinolin-5-yl)acetamido)-4-methylt...)
Affinity DataIC50: 863nMAssay Description:Inhibition of recombinant JNK2 after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50338281(methyl 2-(2-(isoquinolin-5-yl)acetamido)-4-methylt...)
Affinity DataIC50: 31nMAssay Description:Inhibition of recombinant JNK1 after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50338281(methyl 2-(2-(isoquinolin-5-yl)acetamido)-4-methylt...)
Affinity DataIC50: 62nMAssay Description:Inhibition of recombinant JNK3 after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed