BDBM50338262 CHEMBL1682016::N-(4-bromo-3-(1H-1,2,4-triazol-5-yl)thiophen-2-yl)-2-(isoquinolin-5-yl)acetamide

SMILES Brc1csc(NC(=O)Cc2cccc3cnccc23)c1-c1nnc[nH]1

InChI Key InChIKey=GLVDZCDUMFNCFY-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50338262   

TargetMitogen-activated protein kinase 10(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50338262(N-(4-bromo-3-(1H-1,2,4-triazol-5-yl)thiophen-2-yl)...)
Affinity DataIC50: 33nMAssay Description:Inhibition of recombinant JNK3 after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50338262(N-(4-bromo-3-(1H-1,2,4-triazol-5-yl)thiophen-2-yl)...)
Affinity DataIC50: 50nMAssay Description:Inhibition of recombinant JNK2 after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50338262(N-(4-bromo-3-(1H-1,2,4-triazol-5-yl)thiophen-2-yl)...)
Affinity DataIC50: 28nMAssay Description:Inhibition of recombinant JNK1 after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50338262(N-(4-bromo-3-(1H-1,2,4-triazol-5-yl)thiophen-2-yl)...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant p38alpha after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50338262(N-(4-bromo-3-(1H-1,2,4-triazol-5-yl)thiophen-2-yl)...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant ERK2 after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed