BDBM50338237 7-(1-(4-chloro-2-fluorobenzyl)piperidin-3-yl)-2-ureido-5,7-dihydro-4H-thieno[2,3-e]indazole-3-carboxamide::CHEMBL1681985

SMILES NC(=O)Nc1sc-2c(CCc3nn(cc-23)C2CCCN(Cc3ccc(Cl)cc3F)C2)c1C(N)=O

InChI Key InChIKey=LALWIFVAIZGAGQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50338237   

TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Human)
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50338237(7-(1-(4-chloro-2-fluorobenzyl)piperidin-3-yl)-2-ur...)
Affinity DataIC50: 4.10E+4nMAssay Description:Inhibition of human IKK-alpha by substrate phosphorylation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50338237(7-(1-(4-chloro-2-fluorobenzyl)piperidin-3-yl)-2-ur...)
Affinity DataIC50: 500nMAssay Description:Inhibition of human IKK-beta by substrate phosphorylation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed