BDBM50338066 3-(2-(1H-pyrazolo[4,3-b]pyridin-3-yl)-1H-indol-6-yl)-1-cyclopentylprop-2-yn-1-ol::CHEMBL1684668

SMILES OC(C#Cc1ccc2cc([nH]c2c1)-c1n[nH]c2cccnc12)C1CCCC1

InChI Key InChIKey=KJIJZFFBFDJUFT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50338066   

TargetTyrosine-protein kinase ITK/TSK(Human)
Nycomed

Curated by ChEMBL
LigandPNGBDBM50338066(3-(2-(1H-pyrazolo[4,3-b]pyridin-3-yl)-1H-indol-6-y...)
Affinity DataIC50: 300nMAssay Description:Inhibition of recombinant GST-tagged full-length ITK expressed in baculovirus expression system after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed