BDBM50338065 3-(2-(1H-pyrazolo[4,3-b]pyridin-3-yl)-1H-indol-6-yl)-N,N-dimethylprop-2-yn-1-amine::CHEMBL1684667

SMILES CN(C)CC#Cc1ccc2cc([nH]c2c1)-c1n[nH]c2cccnc12

InChI Key InChIKey=CATNPGATOOPPKF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50338065   

TargetTyrosine-protein kinase ITK/TSK(Human)
Nycomed

Curated by ChEMBL
LigandPNGBDBM50338065(3-(2-(1H-pyrazolo[4,3-b]pyridin-3-yl)-1H-indol-6-y...)
Affinity DataIC50: 110nMAssay Description:Inhibition of recombinant GST-tagged full-length ITK expressed in baculovirus expression system after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed