BDBM50337937 5-(2-fluoro-4-iodophenylamino)-3-(3-hydroxypropyl)-8-methylpyrido[2,3-d]pyrimidine-4,7(3H,8H)-dione::CHEMBL1684062::US8470837, 31

SMILES Cn1c2ncn(CCCO)c(=O)c2c(Nc2ccc(I)cc2F)cc1=O

InChI Key InChIKey=SLEMCKVYWPSXMR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50337937   

LigandPNGBDBM50337937(US8470837, 31 | CHEMBL1684062 | 5-(2-fluoro-4-iodo...)
Affinity DataIC50: 5nMpH: 7.3 T: 2°CAssay Description:The inhibitory properties of compounds relative to MEK1 or MEK2 may be determined using a black 384-well-plate format under the following reaction co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2013
Entry Details
Go to US Patent

LigandPNGBDBM50337937(US8470837, 31 | CHEMBL1684062 | 5-(2-fluoro-4-iodo...)
Affinity DataIC50: 4.90nMAssay Description:Inhibition of MEK1 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed