BDBM50337935 5-(2-fluoro-4-iodophenylamino)-3,8-dimethylpyrido[2,3-d]pyrimidine-4,7(3H,8H)-dione::CHEMBL1684060::US8470837, 1

SMILES Cn1cnc2n(C)c(=O)cc(Nc3ccc(I)cc3F)c2c1=O

InChI Key InChIKey=KZRPLGCWNHYBDB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50337935   

LigandPNGBDBM50337935(US8470837, 1 | CHEMBL1684060 | 5-(2-fluoro-4-iodop...)
Affinity DataIC50: 16nMpH: 7.3 T: 2°CAssay Description:The inhibitory properties of compounds relative to MEK1 or MEK2 may be determined using a black 384-well-plate format under the following reaction co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2013
Entry Details
Go to US Patent

LigandPNGBDBM50337935(US8470837, 1 | CHEMBL1684060 | 5-(2-fluoro-4-iodop...)
Affinity DataIC50: 26nMAssay Description:Inhibition of MEK1 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed