BDBM50337923 3-(2-(dimethylamino)ethyl)-5-(2-fluoro-4-iodophenylamino)-8-methylpyrido[2,3-d]pyrimidine-4,7(3H,8H)-dione::CHEMBL1684066::US8470837, 37

SMILES CN(C)CCn1cnc2n(C)c(=O)cc(Nc3ccc(I)cc3F)c2c1=O

InChI Key InChIKey=NGAGTHBIDDBJIY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50337923   

LigandPNGBDBM50337923(US8470837, 37 | CHEMBL1684066 | 3-(2-(dimethylamin...)
Affinity DataIC50: 16nMpH: 7.3 T: 2°CAssay Description:The inhibitory properties of compounds relative to MEK1 or MEK2 may be determined using a black 384-well-plate format under the following reaction co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2013
Entry Details
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LigandPNGBDBM50337923(US8470837, 37 | CHEMBL1684066 | 3-(2-(dimethylamin...)
Affinity DataIC50: 740nMAssay Description:Inhibition of MEK1 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed