BDBM50337920 (R)-3-(2,3-dihydroxypropyl)-5-(2-fluoro-4-iodophenylamino)-8-methylpyrido[2,3-d]pyrimidine-4,7(3H,8H)-dione::CHEMBL1684063::US8470837, 6

SMILES Cn1c2ncn(C[C@@H](O)CO)c(=O)c2c(Nc2ccc(I)cc2F)cc1=O

InChI Key InChIKey=DCUAYYWRCHOBBW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50337920   

LigandPNGBDBM50337920(CHEMBL1684063 | US8470837, 6 | (R)-3-(2,3-dihydrox...)
Affinity DataIC50: 5nMpH: 7.3 T: 2°CAssay Description:The inhibitory properties of compounds relative to MEK1 or MEK2 may be determined using a black 384-well-plate format under the following reaction co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2013
Entry Details
Go to US Patent

LigandPNGBDBM50337920(CHEMBL1684063 | US8470837, 6 | (R)-3-(2,3-dihydrox...)
Affinity DataIC50: 4.60nMAssay Description:Inhibition of MEK1 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed