BDBM50337837 1-(1-(4-chloro-3-fluorophenyl)cyclohexyl)-N,N-dimethylmethanamine::CHEMBL1683888::US10562878, Compound 99

SMILES CN(C)CC1(CCCCC1)c1ccc(Cl)c(F)c1

InChI Key InChIKey=FFPZKPBDKMJMOH-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50337837   

TargetSodium-dependent dopamine transporter(Human)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50337837(1-(1-(4-chloro-3-fluorophenyl)cyclohexyl)-N,N-dime...)
Affinity DataIC50: 17nMAssay Description:Inhibition of human recombinant dopamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50337837(1-(1-(4-chloro-3-fluorophenyl)cyclohexyl)-N,N-dime...)
Affinity DataIC50: 26nMAssay Description:Inhibition of human recombinant Norepinephrine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50337837(1-(1-(4-chloro-3-fluorophenyl)cyclohexyl)-N,N-dime...)
Affinity DataIC50: 145nMAssay Description:Inhibition of human recombinant serotonin transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50337837(1-(1-(4-chloro-3-fluorophenyl)cyclohexyl)-N,N-dime...)
Affinity DataIC50: 145nMAssay Description:Inhibition of human serotonin reuptake transporter was assayed using the recombinant human serotonin transporter expressed in HEK-293 cells. HEK-293 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
Go to US Patent

TargetNeuroepithelial cell-transforming gene 1 protein(Human)
Sunovion Pharamceuticals

US Patent
LigandPNGBDBM50337837(1-(1-(4-chloro-3-fluorophenyl)cyclohexyl)-N,N-dime...)
Affinity DataIC50: 26nMAssay Description:Inhibition of human norepinephrine reuptake transporter was assayed using the recombinant human norepinephrine transporter expressed in either HEK293...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
Go to US Patent

TargetSodium-dependent dopamine transporter(Human)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50337837(1-(1-(4-chloro-3-fluorophenyl)cyclohexyl)-N,N-dime...)
Affinity DataIC50: 17nMAssay Description:Inhibition of human dopamine reuptake transporter was assayed using the recombinant human dopamine transporter expressed in either CHO-K1 or HEK293 c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
Go to US Patent