BDBM50337787 (R)-2-(4-(((S)-3-((R)-3-amino-4-(2,4,5-trifluorophenyl)butanoyl)thiazolidine-2-carboxamido)methyl)phenylamino)-3-methylbutanoic acid hydrochloride::CHEMBL1683506

SMILES CC(C)[C@@H](Nc1ccc(CNC(=O)[C@@H]2SCCN2C(=O)C[C@H](N)Cc2cc(F)c(F)cc2F)cc1)C(O)=O

InChI Key InChIKey=ZUNWVBNRQTWJFD-UHFFFAOYSA-N

Data  6 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50337787   

TargetDipeptidyl peptidase 4(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50337787((R)-2-(4-(((S)-3-((R)-3-amino-4-(2,4,5-trifluoroph...)
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant DPP4 after 60 mins by fluorescence plate readerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetDipeptidyl peptidase 2(Rat)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50337787((R)-2-(4-(((S)-3-((R)-3-amino-4-(2,4,5-trifluoroph...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of rat DPP2 expressed in african green monkey COS7 cells after 60 mins by fluorescence plate readerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50337787((R)-2-(4-(((S)-3-((R)-3-amino-4-(2,4,5-trifluoroph...)
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of human DPP8 expressed in african green monkey COS7 cells after 60 mins by fluorescence plate readerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50337787((R)-2-(4-(((S)-3-((R)-3-amino-4-(2,4,5-trifluoroph...)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of human DPP9 expressed in african green monkey COS7 cells after 60 mins by fluorescence plate readerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetAminopeptidase N(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50337787((R)-2-(4-(((S)-3-((R)-3-amino-4-(2,4,5-trifluoroph...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of APNMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetProlyl endopeptidase(Rat)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50337787((R)-2-(4-(((S)-3-((R)-3-amino-4-(2,4,5-trifluoroph...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of POP in rat brain cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50337787((R)-2-(4-(((S)-3-((R)-3-amino-4-(2,4,5-trifluoroph...)
Affinity DataEC50:  4.08E+5nMAssay Description:Binding affinity to human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed