BDBM50337698 (R)-N-(1-cyanoethyl)-3-(5-(4-((isopropylamino)methyl)phenyl)isoxazol-3-yl)benzamide::CHEMBL1683436

SMILES CC(C)NCc1ccc(cc1)-c1cc(no1)-c1cccc(c1)C(=O)N[C@H](C)C#N

InChI Key InChIKey=GOFDARSHJJLGRM-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50337698   

TargetPkd1(Rat)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50337698((R)-N-(1-cyanoethyl)-3-(5-(4-((isopropylamino)meth...)
Affinity DataEC50:  460nMAssay Description:Inhibition of PKD1 in rat neonatal ventricular myocytes expressing GFP-HDAC5 assessed as inhibition of phosphorylation-dependent HDAC5 nuclear exportMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase D1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50337698((R)-N-(1-cyanoethyl)-3-(5-(4-((isopropylamino)meth...)
Affinity DataIC50: 9nMAssay Description:Inhibition of human PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed