BDBM50337696 (R)-N-(1-cyanoethyl)-3-(5-(4-(4-methylpiperazin-1-yl)phenyl)isoxazol-3-yl)benzamide::CHEMBL1683431

SMILES C[C@@H](NC(=O)c1cccc(c1)-c1cc(on1)-c1ccc(cc1)N1CCN(C)CC1)C#N

InChI Key InChIKey=UBNSODBHXVTOOB-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50337696   

TargetPkd1(Rat)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50337696((R)-N-(1-cyanoethyl)-3-(5-(4-(4-methylpiperazin-1-...)
Affinity DataEC50:  570nMAssay Description:Inhibition of PKD1 in rat neonatal ventricular myocytes expressing GFP-HDAC5 assessed as inhibition of phosphorylation-dependent HDAC5 nuclear exportMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase D1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50337696((R)-N-(1-cyanoethyl)-3-(5-(4-(4-methylpiperazin-1-...)
Affinity DataIC50: 60nMAssay Description:Inhibition of human PKD1 by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed