BDBM50337555 6-(4-(2-methoxyphenyl)piperidin-1-yl)-1-methyl-4-(pyrimidin-4-yl)pyridin-2(1H)-one::CHEMBL1682849

SMILES COc1ccccc1C1CCN(CC1)c1cc(cc(=O)n1C)-c1ccncn1

InChI Key InChIKey=GQTHOMGSRAXQSR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50337555   

TargetGlycogen synthase kinase-3 beta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50337555(6-(4-(2-methoxyphenyl)piperidin-1-yl)-1-methyl-4-(...)
Affinity DataIC50: 51nMAssay Description:Inhibition of human recombinant GSK3-beta expressed in baculovirus infected SF9 cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50337555(6-(4-(2-methoxyphenyl)piperidin-1-yl)-1-methyl-4-(...)
Affinity DataIC50: 3.21E+3nMAssay Description:Inhibition of human GSK3-beta expressed in CHO AA8 cells co-expressing human tau protein after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed