BDBM50337379 CHEMBL1682554::N-butyl-2-(1H-indazol-5-yl)imidazo[1,2-a]pyrimidin-3-amine

SMILES CCCCNc1c(nc2ncccn12)-c1ccc2[nH]ncc2c1

InChI Key InChIKey=ZAOAKWGRHJIYTD-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50337379   

TargetGlycogen synthase kinase-3 beta(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337379(N-butyl-2-(1H-indazol-5-yl)imidazo[1,2-a]pyrimidin...)
Affinity DataKi:  19nMAssay Description:Inhibition of GSK3-betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337379(N-butyl-2-(1H-indazol-5-yl)imidazo[1,2-a]pyrimidin...)
Affinity DataKi:  114nMAssay Description:Inhibition of Pim1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337379(N-butyl-2-(1H-indazol-5-yl)imidazo[1,2-a]pyrimidin...)
Affinity DataKi:  116nMAssay Description:Inhibition of Rock2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PAK 4(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337379(N-butyl-2-(1H-indazol-5-yl)imidazo[1,2-a]pyrimidin...)
Affinity DataKi: >3.75E+3nMAssay Description:Inhibition of Pak4More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337379(N-butyl-2-(1H-indazol-5-yl)imidazo[1,2-a]pyrimidin...)
Affinity DataKi: >4.90E+3nMAssay Description:Inhibition of aurora 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337379(N-butyl-2-(1H-indazol-5-yl)imidazo[1,2-a]pyrimidin...)
Affinity DataKi: >8.88E+3nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed