BDBM50337321 5-(1-(3-methylbenzyl)-1H-1,2,3-triazol-4-yl)-1H-indazole::CHEMBL1682353

SMILES Cc1cccc(Cn2cc(nn2)-c2ccc3[nH]ncc3c2)c1

InChI Key InChIKey=AZRBHUUEXRGWFH-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50337321   

TargetAurora kinase B(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337321(5-(1-(3-methylbenzyl)-1H-1,2,3-triazol-4-yl)-1H-in...)
Affinity DataKi:  15nMAssay Description:Inhibition of Aurora kinase 2 after 1 hr using biotinylated kemptide as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337321(5-(1-(3-methylbenzyl)-1H-1,2,3-triazol-4-yl)-1H-in...)
Affinity DataKi:  70nMAssay Description:Inhibition of GSK3-beta after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337321(5-(1-(3-methylbenzyl)-1H-1,2,3-triazol-4-yl)-1H-in...)
Affinity DataKi:  375nMAssay Description:Inhibition of Rock2 after 1 hr using biotinylated longS peptide as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337321(5-(1-(3-methylbenzyl)-1H-1,2,3-triazol-4-yl)-1H-in...)
Affinity DataKi: >915nMAssay Description:Inhibition of KDR after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed