BDBM50337290 CHEMBL1682209::S-5-Methoxy-9-(3-(4-(3-aminopropyl)piperazin-1-yl)propyl)-7-(2-methoxyacetylamino)-1(1,3),3(1,4),5(1,3)-tribenzena-2-oxa-9-aza-cyclodecaphane

SMILES COCC(=O)N[C@H]1Cc2ccc(OC)c(Cc3ccc(Oc4cccc(CN(CCCN5CCN(CCCN)CC5)C1=O)c4)cc3)c2

InChI Key InChIKey=QXSMBSQHYONEJF-UHFFFAOYSA-N

Data  4 KI  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50337290   

TargetMelanocortin receptor 4(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50337290(S-5-Methoxy-9-(3-(4-(3-aminopropyl)piperazin-1-yl)...)
Affinity DataEC50:  466nMAssay Description:Agonist activity at human MC4 receptor expressed in BHK cells assessed as stimulation of agonist-induced cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50337290(S-5-Methoxy-9-(3-(4-(3-aminopropyl)piperazin-1-yl)...)
Affinity DataEC50:  16nMAssay Description:Agonist activity at human MC1 receptor expressed in BHK cells assessed as stimulation of agonist-induced cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50337290(S-5-Methoxy-9-(3-(4-(3-aminopropyl)piperazin-1-yl)...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human MC3 receptor expressed in BHK cells assessed as stimulation of agonist-induced cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50337290(S-5-Methoxy-9-(3-(4-(3-aminopropyl)piperazin-1-yl)...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human MC5 receptor expressed in BHK cells assessed as stimulation of agonist-induced cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50337290(S-5-Methoxy-9-(3-(4-(3-aminopropyl)piperazin-1-yl)...)
Affinity DataKi:  116nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC1 receptor expressed in BHK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50337290(S-5-Methoxy-9-(3-(4-(3-aminopropyl)piperazin-1-yl)...)
Affinity DataKi:  388nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC5 receptor expressed in BHK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50337290(S-5-Methoxy-9-(3-(4-(3-aminopropyl)piperazin-1-yl)...)
Affinity DataKi:  392nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC4 receptor expressed in BHK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50337290(S-5-Methoxy-9-(3-(4-(3-aminopropyl)piperazin-1-yl)...)
Affinity DataKi:  1.18E+3nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC3 receptor expressed in BHK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed