BDBM50337289 CHEMBL1682208::N-[(13S)-15-{3-[4-(3-aminopropyl)piperazin-1-yl]propyl}-14-oxo-5,7,22-trioxa-15-azapentacyclo[21.2.2.1^{3,11}.1^{17,21}.0^{4,9}]nonacosa-1(25),3(29),4(9),10,17(28),18,20,23,26-nonaen-13-yl]-2-methoxyacetamide

SMILES COCC(=O)N[C@H]1Cc2cc3COCOc3c(Cc3ccc(Oc4cccc(CN(CCCN5CCN(CCCN)CC5)C1=O)c4)cc3)c2

InChI Key InChIKey=FJGOVJXGOUSTAU-UHFFFAOYSA-N

Data  4 KI  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50337289   

TargetMelanocortin receptor 4(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50337289(N-[(13S)-15-{3-[4-(3-aminopropyl)piperazin-1-yl]pr...)
Affinity DataEC50:  697nMAssay Description:Agonist activity at human MC4 receptor expressed in BHK cells assessed as stimulation of agonist-induced cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50337289(N-[(13S)-15-{3-[4-(3-aminopropyl)piperazin-1-yl]pr...)
Affinity DataEC50:  12nMAssay Description:Agonist activity at human MC1 receptor expressed in BHK cells assessed as stimulation of agonist-induced cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50337289(N-[(13S)-15-{3-[4-(3-aminopropyl)piperazin-1-yl]pr...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human MC3 receptor expressed in BHK cells assessed as stimulation of agonist-induced cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50337289(N-[(13S)-15-{3-[4-(3-aminopropyl)piperazin-1-yl]pr...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human MC5 receptor expressed in BHK cells assessed as stimulation of agonist-induced cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50337289(N-[(13S)-15-{3-[4-(3-aminopropyl)piperazin-1-yl]pr...)
Affinity DataKi:  328nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC1 receptor expressed in BHK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50337289(N-[(13S)-15-{3-[4-(3-aminopropyl)piperazin-1-yl]pr...)
Affinity DataKi:  403nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC4 receptor expressed in BHK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50337289(N-[(13S)-15-{3-[4-(3-aminopropyl)piperazin-1-yl]pr...)
Affinity DataKi:  1.53E+3nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC5 receptor expressed in BHK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50337289(N-[(13S)-15-{3-[4-(3-aminopropyl)piperazin-1-yl]pr...)
Affinity DataKi:  4.53E+3nMAssay Description:Displacement of [125I]NDP-alpha-MSH from human MC3 receptor expressed in BHK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed