BDBM50337197 CHEMBL1684876::N3-benzyl-5-((S)-2-((S)-2-(4-cyanobenzamido)-3-(4-hydroxyphenyl)propanamido)-4-methylpentanamido)biphenyl-3,4'-dicarboxamide

SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)c1ccc(cc1)C#N)C(=O)Nc1cc(cc(c1)-c1ccc(cc1)C(N)=O)C(=O)NCc1ccccc1

InChI Key InChIKey=OVGJRTHDFVUONI-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50337197   

TargetSignal transducer and activator of transcription 3(Mouse)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50337197(N3-benzyl-5-((S)-2-((S)-2-(4-cyanobenzamido)-3-(4-...)
Affinity DataIC50: 1.90E+5nMAssay Description:Inhibition of STAT3 dimerization in mouse NIH3T3 cells expressing v-Src assessed as disruption of STAT3-STAT3: DNA complexation in nucleus after 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Mouse)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50337197(N3-benzyl-5-((S)-2-((S)-2-(4-cyanobenzamido)-3-(4-...)
Affinity DataKd:  17nMAssay Description:Inhibition of mouse recombinant SH2 domain of His-tagged full-length STAT3 by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed